Botulotoxín je nervový jed (neurotoxín), ktorý v mieste vpichu blokuje svalové nervy, čím znemožňuje svalové kontrakcie (prácu svalov). Ďalším účinkom botulotoxínu je blokovanie činnosti potných žliaz, v dôsledku čoho sa výrazne znižuje tvorba potu. Tieto účinky predurčujú botulotoxín na liečbu rôznych neurologických a očných ochorení, v estetickej dermatológii na odstraňovanie vrások a korekciu nežiaduceho potenia na dlaniach, chodidlách a v podpazuší. Botulotoxín sa nesmie podávať tehotným a dojčiacim ženám, pri užívaní aminoglykozidových antibiotík a pri ochorení myastenia gravis (autoimunitná svalová slabosť).
Pri aplikácii do podpazuší a dlaní efekt pretrváva 6 – 10 mesiacov. Po zákroku sa potenie redukuje na primeranú mieru. Botulotoxín totiž blokuje iba tzv. ekrinné potné žľazy a neovplyvňuje apokrinné potné žľazy, ktorých je však minimálne množstvo.
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A study of 92 patients withCIDP found a history of preceding infection or some otherprecipitating event in 32% of the cases, and there was asignificantly higher titer for CMV antibodies in the serumof patients with CIDP than in controls (McCombe et al.,1987).The presence of infl ammatory infiltrates in periph-eral nerves and much other experimental data supportsan autoimmune etiology.
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Electron micrograph of cross-section ofthe cilium showing corresponding structureswith drawing below. Moving deeper, these jokes have a finite setof constructs, or building blocks
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Najskôr sa vykoná jódový test. Podpazušie, oblasť triesiel, dlaní alebo chodidiel sa potrie jódom a posype škrobom. V miestach, kde sa zmes jódu a škrobu dostane do kontaktu s potom, dôjde k zreteľnému sčerneniu. Do týchto lokalít sa jemnými vpichmi aplikuje botulotoxín. O dva týždne treba vykonať kontrolu účinnosti ošetrenia (táto je už zahrnutá v cene zákroku).
Ošetrenie na udržanie dosiahnutého výsledku stačí zopakovať spravidla po šiestich mesiacoch.